Deep Vein Thrombosis (DVT) is a condition resulting from the formation of a blood clot (thrombus) inside a deep vein of the leg, commonly located in the calf or thigh. DVT occurs when the blood clot either partially or completely blocks the flow of blood in the vein. Patient symptoms include pain, swelling, and discoloration.
DVT is one part of a disease called venous thromboembolism (VTE). The other part of VTE is the leading cause of preventable hospital death in the United States, Pulmonary Embolism (PE). A PE occurs when a portion of the blood clot breaks off and travels to the lungs, which can lead to death.
Every year there are over 1 million VTE events in Europe and approximately 543 500 related deaths1, more than double of combined deaths due to AIDS (5 860), breast cancer (86 831), prostatecancer (63 636), and transport accidents (53 599).1 The European Countris spends close to $2.4 billion a year to treat DVT.2 Patients with DVT are typically treated with anticoagulation therapy alone, such as a blood thinner. While blood thinners are effective in reducing the risk of a fatal pulmonary embolism and growth of the blood clot, the underlying blood clot may remain and result in permanent vein damage, which could lead to the development of post thrombotic syndrome.